(E)-3-[3-(Trifluoromethyl)phenyl]acryloyl chloride, (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoyl chloride, 3-[(1E)-3-Chloro-3-oxoprop-1-en-1-yl]benzotrifluoride
trans-3-(trifluoromethyl)cinnamoyl chloride
CAS: 64379-91-5
Molecular Formula: C10H6ClF3O
(E)-3-[3-(Trifluoromethyl)phenyl]acryloyl chloride, (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoyl chloride, 3-[(1E)-3-Chloro-3-oxoprop-1-en-1-yl]benzotrifluoride - Names and Identifiers
(E)-3-[3-(Trifluoromethyl)phenyl]acryloyl chloride, (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoyl chloride, 3-[(1E)-3-Chloro-3-oxoprop-1-en-1-yl]benzotrifluoride - Physico-chemical Properties
| Molecular Formula | C10H6ClF3O |
| Molar Mass | 234.6 |
| Density | 1.372g/mLat 25°C(lit.) |
| Melting Point | 28-31℃ |
| Boling Point | 148°C60mm Hg(lit.) |
| Flash Point | 201°F |
| Vapor Presure | 0.0575mmHg at 25°C |
| Storage Condition | dry |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.544(lit.) |
| MDL | MFCD00075514 |
(E)-3-[3-(Trifluoromethyl)phenyl]acryloyl chloride, (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoyl chloride, 3-[(1E)-3-Chloro-3-oxoprop-1-en-1-yl]benzotrifluoride - Risk and Safety
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R26 - Very Toxic by inhalation |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| Hazard Note | Harmful |
| Hazard Class | 8 |
| Packing Group | III |
(E)-3-[3-(Trifluoromethyl)phenyl]acryloyl chloride, (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoyl chloride, 3-[(1E)-3-Chloro-3-oxoprop-1-en-1-yl]benzotrifluoride - Introduction
trans-3-(trifluoromethyl)cinnamoyl chloride is an organic compound with a chemical formula of C10H6ClF3O and a molecular weight of 234.6g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow liquid.
-Melting point: 44-47°C.
-Boiling point: 266-267°C.
-Density: 1.394 g/ml.
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane.
-Stability: sensitive to moisture and light.
Use:
trans-3-(trifluoromethyl)cinnamoyl chloride is an important intermediate in organic synthesis and is often used in the synthesis of biologically active compounds. It can be used in the synthesis of organic photoelectric materials, drug synthesis and pesticide synthesis.
Preparation Method:
trans-3-(trifluoromethyl)cinnamoyl chloride can be prepared by the following methods:
1. cinnamic acid is reacted with trifluoroformic acid in the presence of an acidic catalyst (such as sulfuric acid) to obtain m-trifluoromethyl cinnamic acid.
2. m-trifluoromethylcinnamic acid reacts with thionyl chloride to give trans-3-(trifluoromethyl)cinnamoyl chloride.
Safety Information:
trans-3-(trifluoromethyl)cinnamoyl chloride should pay attention to the following safety matters during operation:
-Wear appropriate protective gloves, glasses and protective clothing.
-Avoid breathing its vapors.
-Avoid contact with skin and eyes, such as contact should be washed with water immediately.
-Operate in a well-ventilated environment.
-Storage should be sealed and kept away from fire and oxidizing agents.
Please note that when using any organic compound, you should use caution and strictly follow safe operating procedures. When handling and storing chemical substances, the relevant safety data sheets and operating instructions should be carefully read and understood.
Nature:
-Appearance: Colorless to light yellow liquid.
-Melting point: 44-47°C.
-Boiling point: 266-267°C.
-Density: 1.394 g/ml.
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane.
-Stability: sensitive to moisture and light.
Use:
trans-3-(trifluoromethyl)cinnamoyl chloride is an important intermediate in organic synthesis and is often used in the synthesis of biologically active compounds. It can be used in the synthesis of organic photoelectric materials, drug synthesis and pesticide synthesis.
Preparation Method:
trans-3-(trifluoromethyl)cinnamoyl chloride can be prepared by the following methods:
1. cinnamic acid is reacted with trifluoroformic acid in the presence of an acidic catalyst (such as sulfuric acid) to obtain m-trifluoromethyl cinnamic acid.
2. m-trifluoromethylcinnamic acid reacts with thionyl chloride to give trans-3-(trifluoromethyl)cinnamoyl chloride.
Safety Information:
trans-3-(trifluoromethyl)cinnamoyl chloride should pay attention to the following safety matters during operation:
-Wear appropriate protective gloves, glasses and protective clothing.
-Avoid breathing its vapors.
-Avoid contact with skin and eyes, such as contact should be washed with water immediately.
-Operate in a well-ventilated environment.
-Storage should be sealed and kept away from fire and oxidizing agents.
Please note that when using any organic compound, you should use caution and strictly follow safe operating procedures. When handling and storing chemical substances, the relevant safety data sheets and operating instructions should be carefully read and understood.
Last Update：2024-04-09 15:17:59
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Product Name: trans-3-(Trifluoromethyl)cinnamoyl chloride Visit Supplier Webpage Request for quotation
CAS: 64379-91-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 64379-91-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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